Lepra tuberculoide. Rios González, Carlos Miguel Cátedra de Dermatología. Facultad de Ciencias Médicas. Universidad Nacional de Caaguazú. Paraguay. El 65,4 % de los casos índices fueron hombres y 22 (84,6 %) lepromatosos; dos tenían lepra indeterminada y dos tuberculoide. Los casos secundarios fueron. La lepra o malaltia de Hansen és una malaltia infectocontagiosa però difícilment . que estaran engruixits i es podran palpar, sobretot a la lepra tuberculoide.

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International Journal of Osteoarchaelogy ; 2: He lives with his wife, a daughter and five grandchildren. They may take the form of multiple nodules lepromas that progress to necrosis and ulceration. Chromosome 6q25 is linked to susceptibility to leprosy in a Vietnamese population. Nevertheless, much remains to be known about the mechanism of interaction between the two diseases and further research is required.

The lepar areas anaesthetised by the nerve infection are susceptible to tissue infection. Acid-fast bacilli in semen; correlation with bacterial index. Full text available only in PDF format. This multibacillary clinical form is known as lepromatous leprosy. Should household contact examination in a low endemic situation of leprosy continue? Weekly Epidemiological Record22 May. Smithsonian Institution Press; The lepromin reaction and histology indicate that these patients show a cell-mediated immune response, or delayed hypersensitivity, tubercu,oide occurs in tuberculosis.

Its preference for cooler anatomical regions means that vital organs are usually preserved, but also makes leprosy a disease that slowly destroys the distal areas of fingers and toes and causes nasal and facial deformities that lead to social marginalization.

Saúde Pública – Lepra Conyugal Lepra Conyugal

Oral lesions in leprosy. Quinolones, such as ofloxacin and pefloxacin, as well as some macrolides, such as clarithromycin and minocyclin are also effective 6. However, the absence of a granulomatous tuberculoidd or inflammatory response reduces the tissue destruction characteristic of the tuberculoid form. Once signs have appeared the disease will generally progress slowly unless treated.

Under these circumstances the clinical form begins to acquire certain lepromatous characteristics, with aspects of BL, the intermediate form or, more rarely, BT. The presence, in the subcutis of lepers, of metamorphosic forms of HANSEN bacillus, is the cause of common relapses of negativated cases by treatment, which fact suggests a new therapeutics method to destroy such elements in loco, and exiges more strict examination before tubwrculoide of interned patients.


The differential diagnosis includes systemic lupus erythematosus, sarcoidosis, cutaneous leishmaniasis and other skin diseases, tertiary syphilis, lymphomas, systemic mycosis, traumatic lesions tuberculoie malignant neoplasias, among other disorders. However, those which settle in the internal organs are usually effectively eliminated by macrophages.

Lepra infantil: Presentación de un caso (Childhood leprosy: Report of a case)

He is being monitored by his general practitioner and receives domiciliary care for his left knee lesions and diabetes. It is transmitted from person to person and has a long incubation period between two and six years. Around one-third of people with leprosy present the first clinical manifestations during childhood.

Impact of MDT on incidence rates of leprosy among household contacts. The lesions are usually located on the hard and soft palate, in the uvula, on the underside of the tongue, and on the lips and gums. In other cases the bone involvement is secondary to peripheral neuropathy. The nasal mucosa become ulcerated and form scabs. This consists in the intradermal injection of lepromin extract of the leprous leprx taken from sick patients.

Clinical aspects of leprosy. Such bacteriological findigs and the proved mutation of tuberculoid leprosy into lepromatous type, demolished the basis of the so-called “polar” classification of leprosy. There were suppurating ulcers on the right trochanter and at the head of the left fibula.

This was not the case of the patient tubecruloide here, who maintained sensitivity.

The patient reported here suffered both bilateral blindness and leonine facies Figure 1. ReadCube Visualizar o texto. Domiciliary care to be arranged for treating the ulcers. They were aged from 20 to Nature Genet ; A hard and rigid irregular nerve trunk is sometimes observed in the more superficial areas of the elbow cubital nerve or at the head of the fibula peroneal nerve.


Int J Dermatol ; Rev Leprol Fontilles ; It is usually negative in lepromatous leprosy and positive in the tuberculoid form.

Hansen Neuropathy: Still a Possible Diagnosis in the Investigation of a Peripheral Neuropathy.

Mycobacterium leprae, lepromatous leprosy, tuberculoid leprosy, differential diagnosis. There were some pigmented tubeerculoide on the distal third of the hard palate; the rest of the mucosa showed a normal appearance Figures 2 and 3. Correlation of oral surface temperatures and the lesions of leprosy. Although the position of a given patient on this spectrum is relatively stable the le;ra response which characterises tuberculoid leprosy may deteriorate in untreated patients, especially in those who suffer malnutrition tubeerculoide other infections Dermatol Rev Mex ; Evolution of the disease: Andersen JG, Manchester K.

He suffered from protein-energy malnutrition. Lepromatous leprosy usually begins in the form of chronic rhinitis. The differential diagnosis includes systemic lupus erythematosus, sarcoidosis, cutaneous leishmaniasis and other skin diseases, tertiary syphilis, cicatricial pemphigoid, lethal midline granuloma, lymphomas, systemic mycosis, traumatic lesions and malignant neoplasias, as well as peripheral nerve pathology such as syringomyelia, among other disorders 2,6.

This loss of maxillary bone structures and teeth constitutes another characteristic facial alteration in leprosy 4which in the case of our patient contributed to the leonine appearance of the lip Tubberculoide 2.

Studying by a new thecnics, which he baptised before as “Lleras’ method”, the scarching of the agent of leprosy in tuberculoid cases, by examination of sub-corium lymph obtained from the lesion, he discovered new forms of the Hansen bacillus, which describes briefly, arriving at the following conclusions: Reproducido en Rev Leprol Fontilles ; Therefore, it seemed of interest to review the topic by means of a highly representative clinical case.